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Image Search Results
Journal: Scientific Reports
Article Title: The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples
doi: 10.1038/s41598-020-66062-1
Figure Lengend Snippet: Flow diagram detailing sample collection and study design. We identified candidate plasma microRNAs in treatment naive patients newly diagnosed with DLBCL. The samples were collected as previously described . The deregulated microRNAs were subsequently used for screening of individuals later diagnosed with DLBCL, FL or HL from the DBDS cohort. *The 16 cases were picked because they had previously been examined using expression array on tumor. **The controls could not be matched completely because the DBDS cohort was limited to age 18–67 years. Consequently we selected random controls.
Article Snippet: Based on these initial results, a targeted screening panel including 11 different
Techniques: Expressing
Journal: Scientific Reports
Article Title: The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples
doi: 10.1038/s41598-020-66062-1
Figure Lengend Snippet: Screening cohort tumor microRNA expression a ) and b ). Expression levels in tumor of relevant microRNAs are plotted as intensity (median, 25% and 75% percentiles). Array data were normalized using robust multi-array average. Up-regulated c ) and Down-regulated d ) plasma microRNAs plotted as fold change (2 −ΔΔCt ) difference between cases and controls (median, 25% and 75% percentiles). RT-PCR data were normalized using miR-23a. Statistically significant difference (<0.0003) between cases and controls adjusted for age and sex in quantile regressions is marked with a * .
Article Snippet: Based on these initial results, a targeted screening panel including 11 different
Techniques: Expressing, Reverse Transcription Polymerase Chain Reaction